SAA is a sensitive inflammatory marker discovered in recent years. As an acute-phase reactive protein, its concentration increases significantly in acute and chronic inflammatory reactions, reaching more than 1000 times the normal level in 6-8 hours. As SAA has a short half-life, when the body’s inflammatory response is controlled, SAA rapidly drops to the normal level, which makes SAA a sensitive indicator of the body’s inflammatory state such as infection or trauma. In normal conditions, SAA concentration in serum is approximately 1-10 μ g/ml. However, during an acute-phase reaction, the concentration can rise to 1 mg/mL or even higher. SAA can be used in diagnosis, predicting outcomes and assessing the efficacy of treatment in patients with inflammation.
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