Transferrin (TRF) Rapid Test Kit

Release date： 2026-01-29 17:05:23 Readings： 0 Author： admin

The Transferrin (TRF) Rapid Test is a rapid chromatographic immunoassay (non-invasive assay) for the qualitative detection of human transferrin in human feces specimens, which might be useful for the diagnosis of bleeding gastrointestinal disorders.

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Transferrin is a β-globulin, synthesized primarily in the liver, which is the principal protein responsible for iron transport. Transferrin is a blood plasma protein for iron ion delivery and is undetectable in normal human gastrointestinal tract. Detection of transferrin in feces or contents in the stomach indicates bleeding in gastrointestinal tract. A patient with an increased serum transferring level suffers from iron deficiency anaemia that is one of the most important symptoms when a tumour has caused chronic occult bleeding. It has been reported that fecal transferrin is elevated in patients with colorectal tumor, compared to healthy individuals. Recently, a number of proteomic studies showed that transferrin could be used as a marker expressing in a number of cancers.

Unlike hemoglobin, transferrin is still detectable once released into the upper gastrointestinal tract. And transferrin is resistant to degradation by digestive enzymes and bacteria. Thus, compared to hemoglobin, transferrin is more stable in feces making transferrin an ideal marker for detecting the loss of blood from both the upper and lower intestine (gastrointestinal bleeding).

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